Get unexpected emergency healthcare assistance For those who have indications of an allergic reaction to Roxicodone: hives; problems breathing; swelling of your respective face, lips, tongue, or throat.CYP450 3A4 Conversation: The concomitant use with CYP450 3A4 inhibitors (or discontinuation of CYP450 3A4 inducers) may end in a deadly overdose of